World AIDS Vaccine Day takes place on May 18, 2017. The day, also known as HIV Vaccine Awareness Day, is observed annually. HIV Vaccine advocates mark the day by promoting the continued urgent need for a vaccine to prevent HIV infection and AIDS. The first World AIDS Vaccine Day was observed on May 18, 1998, to commemorate the anniversary of Clinton’s speech, and the tradition continues today. Each year communities around the globe hold a variety of activities on World AIDS Vaccine Day.